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Isaac Davis THOMPSON, M.D.
Mary Jane SORRELL
Husband:  Isaac Davis THOMPSON
Birth:  11 Mar 1818 or 3 Nov 1818, Christian [now Todd] Co., KY
Death:  17 Sep 1856, presumably Mercer Co., MO
Disposition:  buried Middlebury Cemetery, Mercer Co., MO
Occupation:  physician
Fraternal:  Mason 
Father:  Thomas THOMPSON
Mother:  Delilah DAVIS
Marriage:  25 Dec 1836, Randolph Co., MO
Wife:  Mary Jane SORRELL
Birth:  26 Nov 1818, KY
Death:  in or aft. 1880, probably in Mercer Co., MO
Father possibly:  John SORRELL, Sr. (1780s- )

A secondary source says she was born in VA and died on 16 Sep 1866, which is obviously incorrect.

Children — born in Randolph Co., MO:
1.  Ann E. THOMPSON, 1837/8; m. Mr. COX
2.  Martha THOMPSON, b. 1839/40; m. Mr. MAY
3.  John Thomas F. THOMPSON, b. 1843
4.  Nancy M. THOMPSON, b. 1845/6
5.  Mary THOMPSON, b. 1846/7
6.  S. Delilah THOMPSON, b. 1848/9
7.  James A. THOMPSON, b. 7 Mar 1852
8.  George R. THOMPSON, b. 1854/5

A secondary source has these six children for them:  Martha Frances (b. 28 Feb 1844), Anne, Nancy M., James A. (7 Mar 1852), George, and John Thomas.

Keywords for search engines:  genealogy; USA, US, United States, Kentucky Missouri, Virginia

ANNOUNCEMENT:  There is a mailing list for researchers of the genealogy and family history of Thomas THOMPSON and kin, including his sister, Rachel THOMPSON and her husband, William T. WYATT, and the ancestors of Thomas's wife, Delilah DAVIS.  Please join and share in the research.  To subscribe, visit this web page and follow the instructions.

Sources:

1.  Family Group Sheet by Betty Ann (Matthiesen) Cogliati and her grandmother, Maude Irene (Thompson) Rose.  Their sheet did not include any children.

2a.  Jordan R. Dodd, ed.  1994.  Missouri Marriages: Early to 1850.  Liahona Res., Orem, UT (Broderbund CD-227):
Thompson, Isaac Sorrell, Mary Jane Dec 25, 1836 Randolph Co.

2b.  Marriage Records of Randolph County, Missouri (lookup courtesy of Pamela Creighton).  In Book A. on p. 33 :
Isaac D. Thompson and Mary Jane Sorrell, 25-Dec-1836, by Thomas Thompson, JP

3.  1840 Census Index and Digital Images (online at Ancestry.com; Image #9-10 of 64; extracted by Diana Gale Matthiesen):¤
1840 MO Randolph Co. Row 229 p. 271 Line 22 Isaac D Tompson 000 010 - 100 010 no slaves 0100000
These data indicate:
No. & Sex Age Class Therefore Born Individuals Inferred
1 male 20-29 1810-1820 = Isaac (b. 1817)
1 female 4 or under 1835-1840 = Anne (b. 1837/8)
1 female 20-29 1810-1820 = Mary Jane (b. 1818)
1 person engaged in agriculture
Listed 10 lines from John SORRELL, Sr., who is said to be Mary Jane's father.

4a.  1850 Census Index/Microfilm (online at GenealogyLibrary.com):  "Hotel," El Dorado Co., CA, p. 378, 6/6, enumerated 24 Oct 1850, official enumeration date 1 Jun 1850 (extracted by Diana Gale Matthiesen):
Thomas Thompson 48 M Hotel 4200 Ky
Mildred   " 43 F     "
Isaac D.  " 33 M Physician   "
[siblings and lodgers]          
Thomas is Isaac's father.  Isaac appears to have left his family back home — and, in so doing, managed to get himself enumerated twice.  Was he in California to provide medical services to Thomas's "flock"?  Or had he caught "gold fever"?

4b.  1850 Census Index/Images (online at Ancestry.com; Image #30 of 43):  Prairie Twp., Randolph Co., MO, p. 261A, 866/866, enumerated 5 Nov 1850, official enumeration date 1 Jun 1850 (extracted by Diana Gale Matthiesen):
I D Thompson 32 M   Farmer   Ky
Mary J   " 31 F       "
Ann      " 12 F       Mo
Martha   " 10 F       "
John     "  7 M       "
Nancy    "  5 F       "
Mary     "  3 F       "
Delila   "  1 F       "

5.  1860 Census Images (online at Ancestry.com; Image #12 of 41):  Modena P.O., Madison Twp., Mercer Co., MO, p. 304, PN 204, 1433/1433, enumerated 23 Jul 1860, official enumeration date 1 Jun 1860 (extracted by Diana Gale Matthiesen):
Mary J Thompson 42 F     1600 600 Kentucky
Ann E      " 22 F         Missouri
Thomas F   " 16 M   Farm Laborer     "
N M        " 13 F         "
S D        " 11 F         "
J R        "  8 M         "
G R        "  5 M         "

6.  1870 Census Images (online at Ancestry.com; Image #86 of 301):  Goshen City, Madison Twp., Mercer Co., MO, p. 112B, PN 22, 149/148, enumerated 13 Aug 1870, official enumeration date 1 Jun 1870 (extracted by Diana Gale Matthiesen):
Thompson Mary J 51 F W Keeping House 2400 650 Kentucky
________ Thomas 26 M W Teacher     Missouri
________ Nancy M 24 F W Teacher     Missouri
________ James A 18 M W works on farm     Missouri
________ George R 15 M W At Home     Missouri

7.  1880 United States Census and National Index (LDS Family History Resource File: CD-ROM Library):
Census Place: Princeton, Mercer, Missouri
Source: FHL Film 1254703; NARA Film T9-0703; Pg 70A
  Relation Sex Marr Race Age Birthplace Occupation Fa Mo
Mary J. THOMPSON Wife F W W 61 KY   VA VA
Nancy M. THOMPSON Dau F S W 31 MO Teaching MO KY
James A. THOMPSON Son M S W 28 MO Circurt Clerk MO KY
George R. THOMPSON Son M S W 25 MO Teaching School MO KY
The children's father was born in KY, not MO.

8.  Mrs. B.F. Hoover & Mrs. D. Hesler.  1965.  Middlebury Cemetery, Mercer County, MO (online at the Grundy County MOGenWeb site):
THOMPSON, Dr. I.D. 17 Sep 1856 38y, Mason; stone is down

9.  Betty Cogliati sent me a photocopy of a page of what appear to be will abstracts of Mercer Co., MO (if anyone knows the full citation for this source, please let me know what it is).  On p. 88:
THOMPSON, ISAAC D., died intestate.  Admrx., Mary Jane Thompson. Sec., Wm. Reid & John (J.A.C.) Thompson. 10 Nov 1865. (A78-79)
The settlement of Isaac's estate took years because Isaac had so much property and so many creditors, not because of conflicts among the family.

10.  LDS.  Family Search: Internet Genealogy Service:  IGI - International Genealogical Index (online at FamilySearch.org).

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