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Conrad NULL
Ms. __?__
Margaret CUPP
Mrs. Catharine (__?__) DOWNHOUSE
Husband:  Conrad NULL / NOLL
Birth:  1780
Death:  bef. 18 Sep 1848
Marriage-1:
Wife-1:  Ms. __?__
Based on the 1830 Census (see below), it appears Conrad had a wife before Margaret, and given Conrad's age, we would expect that he did.  Either that or the 1826 marriage date really is 1816.
Marriage-2:  29 Aug 1826, Augusta Co., VA, but said to be in 1816
Wife-2:  Margaret "Peggy" CUPP
Birth:  20 Apr 1789, Augusta Co., VA
Death:  1840-42, Perry Co., OH
Occupation:  homemaker
Father:  Marcus CUPP
Mother:  Margaretha __?__
Marriage-3:  12 Apr 1842, Perry Co., OH
Wife-3:  Catharine __?__
Birth:  1806/7, OH
Death: aft. 18 Sep 1848
Occupation:  homemaker
Other Spouse:  m1. Mr. DOWNHOUSE/DOWNHOUR/DOWNER
Other Children:
1.  Bernard DOWNHOUSE, b. 1833/4, OH
2.  Henry DOWNHOUSE, b. 1838/9, OH
Child with Wife-1:
1.  (Son? A) NULL, b. 1820-25
Children with Margaret CUPP:
apparently none
Children with Catharine:
2.  Anna/Ann Catherine NULL, b. 1842/3
3.  Susannah "Susan" NULL, b. 1844/5
4.  Lucinda NULL, b. 1848


Sources:

1a.  Jordan R. Dodd, ed.  1993.  Virginia Marriages:  Early to 1850.  Liahona Research, Orem, UT (Broderbund CD-229):
Noll, Conrad Cupp, Peggy Aug 29, 1826 Augusta Co.
There is reason to believe this transcription is a typo and that they were married in 1816, not 1826.

1b.  LDS.  Family Search: Internet Genealogy Service: IGI - International Genealogical Index (online at FamilySearch.org).
Conrad NULL
Spouse: Catharine DOWNHOUR
Marriage: 12 Apr 1842, Perry, Ohio
Source: patron submission

2.  Census Index:  U.S. Selected Counties, 1820 (Broderbund CD-314):  can't find.  (He's not either of the C. NULLs in OH.)

3.  1830 Census Index and Digital Images (online at Ancestry.com; Image #3 of 20; extracted by Diana Gale Matthiesen):¤
1830 OH Perry Co. Thorn Twp. p. 417 Ln. 14 Conrad Null 010 001 010 - 000 000 100
These data indicate:
No. & Sex  Age Class Therefore Born Individuals Inferred
1 male 5-9 1820-1825 = Son A
1 male 30-39 1790-1800 = ?
1 male 50-59 1770-1780 = Conrad (b. 1780)
1 female 40-49 1780-1790 = Margaret (b. 1789) 
"Son A" was born before Margaret and Conrad married, so it appears Conrad had an earlier wife unless their marriage date is wrong.

4.  1840 Census Index and Digital Images (online at Ancestry.com; Image #5-6 of 20; extracted by Diana Gale Matthiesen):¤
1840 OH Perry Co. Thorn Twp. pp. 58B-59A Ln. 1 Coonrod Null 000 100 010 - 000 000 010 0200000
These data indicate:
No. & Sex Age Class Therefore Born Individuals Inferred
1 male 15-19 1820-1825 = Son A
1 male 50-59 1780-1790 = Conrad (b. 1780)
female 50-59 1780-1790 = Margaret (b. 1789)
2 persons engaged in agriculture

5.  1850 Census Index/Images (online at Ancestry.com; Image #24 of 44):  Thorn Twp., Division No. 117, Perry Co., OH, p. 408B/816, 1258/1258, enumerated 16 Oct 1850 (extracted by Diana Gale Matthiesen):
Catharine Null 43 F     Ohi
Bernard Downhouse 16 M Farmer 800 Ohi
Henry       " 11 M     do
Ann C Null  7 F     do
Susan   "  5 F     do
Luzinda "  1 F     do
Bernard and Henry must be Catharine's children by her first marriage.

6.  Rosalie Hartinger, contributor.  1989.  "Perry County, Ohio Will Abstracts 1818-1851."  Vol. II, pp. 353-381, in Ruth Bowers & Anita Short.  Gateway to the West.  2 vols. Genealogical Publ. Co., Baltimore, MD (Broderbund CD-175).  On p. 372:
NULL, Conrad - dated 9-18-1848.  Wife, Catherine.  Mentions deceased wife, Margaret.  Children: Anna Catherine, Susannah and Lucinda.  Executors: John and Samuel Cupp.  Witnesses:  Emanuel Fisher and Wm. Dempsey. (257)

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