1.  LDS.  Family Search: Internet Genealogy Service:  IGI - International Genealogical Index (online at FamilySearch.org).

David S. HOPKINS Spouse: Mary A. PATTERSON Marriage: 09 Dec 1858, Kalamazoo, Michigan Source: Marriage Records, 1831-1950. Kalamazoo County (Michigan). County Clerk

David S. HOPKINS Spouse: Florence E. MINICK Marriage: 22 Jul 1875, Stark, Ohio Source: Marriage Records, 1809-1916. Ohio. Probate Court (Stark County)

2.  1850 Census Every-Name-Index/Images (online at Ancestry.com):  David HOPKINS (æ 14, b. NY) is living in Washington Co., NY, with his father (q.v.).  Mary A. EATON (æ 15, b. MI) is living in Kalamazoo, Kalamazoo Co., MI , with her step-parents, George & Rebecca PATTERSON (q.v.).

3.  1860 Census Every-Name-Index/Images (online at Ancestry.com, Image #53 of 176):  Kalamazoo P.O., Village of Kalamazoo, Kalamazoo Co., MI, Roll M653_548, p. 459, PN 53, 387/384, enumerated 20 Jun 1860, official enumeration date 1 Jun 1860 (extracted by Diana Gale Matthiesen):

David S Hopkins	25	M		Carpenter Master		200	New York
May A      "	24	F					Michigan
George P   "	9/12	M					"
George Patterson	59	M		Farmer	3000	500	Pennsylvania
John McPherson	25	M		Carpenter			Canada
Betsey Waller	17	F					Ohio

4a.  1870 Census Index/Images (online at Genealogy.com, Image #59-60 of 121):  Grand Rapids P.O., Grand Rapids (Ward 2), Kent Co., MI, Roll 681, pp. 286A-286B, PN 59-60, 437/430, enumerated 2 Jul 1870, official enumeration date 1 Jun 1870 (extracted by Diana Gale Matthiesen):¤

Scruby Melinda	51	F	W	Keeping House		900	Ohio
______ Emma	22	F	W				Wisconsin
______ Elizabeth	19	F	W				Wisconsin
______ George	13	M	W	At School			Wisconsin
[next page]
Hopkins David S	30	M	W	Architect		1500	New York
Hughes Edwin H	23	M	W	Ticket Agent			Michigan
Seales George	23	M	W	Printer			Michigan
Ladd John L	24	M	W	Book Keeper			New York
Fay Franklin	26	M	W	Carpenter		125	New York
Murphy William	35	M	W	Carpenter		100	New York

David should be 35, not 30.  Melinda SCRUBY's maiden name was HOPKINS, so my first thought was that they were related; however, the surnames appear to be a coincided because these are two different HOPKINS families, with two different progenitors.

4b.  1870 U.S. Census Every-Name-Index/Images (online at Ancestry.com, Image #107-108 of 266):  Kalamazoo P.O., Kalamazoo Village, Kalamazoo Co., MI, Roll M593_680, pp. 174B-175A, PN 74-75, 505/488, enumerated 29 Jun 1870, official enumeration date 1 Jun 1870 (extracted by Diana Gale Matthiesen):

Hopkins Wm D	43	M	W	Carpenter			New York
[next page]
Patterson George	67	M	W	Carpenter		5000	Virginia
Hopkins Mary A	34	F	W	Keeping House	2500		Michigan
_______ Frank	7	M	W	At school			Michigan
_______ Charles	5	M	W				Michigan

Where are sons George and Irving?

5a.  1880 Census Every-Name-Index/Images (online at Ancestry.com, Image #31 of 55):  406 Jefferson Avenue, Grand Rapids (Ward 3), Kent Co., MI, Roll T9-0588, p. 346C, PN 31, SD 2, ED 140, enumerated 11 Jun 1880, official enumeration date 1 Jun 1880 (extracted by Diana Gale Matthiesen):

1880:  for an explanation of the column headings, please see What the Numbers in the Federal Census Mean (missing columns contained no data).
		1	2	3	4	5	6	8	10	13	24	25	26
*	406	304	347	Hopkins David S	W	M	45		/	Architect	NY	NY	NY
				_______ Florence F	W	F	30	Wife	/	Keeping House	OH	Ger	Eng
*Jefferson Ave

5b.  1880 U.S. Census Every-Name-Index/Images (online at Ancestry.com, Image #44 of 99):  49 Dutton Street, Kalamazoo, Kalamazoo Co., MI, Roll 586, p. D, PN 44, SDD 1, ED 134, enumerated 14 Jun 1880, official enumeration date 1 Jun 1880 (extracted by Diana Gale Matthiesen):

1880:  for an explanation of the column headings, please see What the Numbers in the Federal Census Mean (missing columns contained no data).

1

2

3

4

5

6

8

9

10

11

13

21

24

25

26

*

49

446

471

Patterson George

W

M

77

none

/

Deputy Sheriff

VA

PA

PA

Hopkins Mary A

W

F

43

Dau

/

Keeping house

MI

VA

OH

_______ Frank B

W

M

17

GSon

/

Attends School

/

MI

NY

MI

_______ Charles H

W

M

14

GSon

/

Attends School

/

MI

NY

MI

*Dutton Street

6.  1890 Census:  the 1890 Census Population Schedules were destroyed.

7.  1900 Census Every-Name-Index/Images (online at Ancestry.com, Image #41 of 50):  113 Paris Ave., Grand Rapids (Ward 3), Kent Co., MI, Roll T623_721, p. 329A, SN 21, SD 5, ED 54, enumerated 1 Jun 1900, official enumeration date 1 Jun 1900 (extracted by Diana Gale Matthiesen):

1900:  for an explanation of the column headings, please see What the Numbers in the Federal Census Mean (missing columns contained no data).

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

16

17

18

19

20

21

22

23

24

27

*

113

466

488

Hopkins David S

Head

W

M

Sep 1834

65

M

20

NY

RI

NY

Y

Y

Y

H

_______ Florence

Wife

W

F

Feb 1862

38

M

20

1

1

OH

Ger

OH

At School

10

Y

Y

Y

_______ Hazel M

Dau

W

F

Jul 1888

11

S

MI

NY

OH

Y

Y

Y

M?nnich Nicholus

Father in L

W

M

Dec 1821

78

Wd

Ger

Ger

Fra

1850

50

Na

Y

Y

Y

Lobdell Charles

Coachman

W

M

May 1877

23

S

MI

MI

MI

Coachman

0

Y

Y

Y

*Paris Ave

Florence is fibbing big time about her age, and to support her age (50, not 38), she's lied about how long she's been married (25 yrs, not 20); she's back to reality in 1910.

8.  1910 Census Index/Images (online at Ancestry.com, Image #25 of 29):  113 Paris Ave., Grand Rapids (Ward 3), Kent Co., MI, Roll T624_656 (Part 2), p. 115A, SN 12A, SD 5, ED 60, enumerated 21 Apr 1910, official enumeration date 15 Apr 1910 (extracted by Diana Gale Matthiesen):

1910:  for an explanation of the column headings, please see What the Numbers in the Federal Census Mean (missing columns contained no data).
		1	2	3	4	5	6	7	8	9	10	11	12	13	14	17	18	23	24	25	26	27	28
*	113	216	224	Hopkins David S	Head	M	W	75	M2	35			NY	New York	NY	Eng	Own Income	Y	Y		O	F	H
				_______ Florence A?	Wife	F	W	59	M1	35	1	1	OH	Ger-German	US	Eng	None	Y	Y
				_______ Hazel M	Dau	F	W	22	S				MI	New York	OH	Eng	None	Y	Y	Y
*Paris Ave

9.  1920 Census Index/Images (online at Ancestry.com):  can't find.

.  State of Michigan: Death Certificate: David S. Hopkins (image courtesy of Nicole Bray):

.  Find-a-Grave: Entries (online at FindaGrave.com):

Name	David S. Hopkins	Mary A Eaton Hopkins	-	-	-	-	-	-	-	-
Birth	1834	1836	-	-	-	-	-	-	-	-
Death	1918	1 Dec 1922	-	-	-	-	-	-	-	-
Note	Architect. Son of Charles S. and Elizabeth (Betsey) Williams Hopkins. Father of Hazel, Irving and George P. Divorced from first wife Mary, who died in Muskegon where she lived with their son Irving Hopkins.	-	-	-	-	-	-	-	-	-
Burial	Oakhill Cemetery Grand Rapids, Kent County, Michigan	Oakwood Cemetery Muskegon, Muskegon County, MI	-	-	-	-	-	-	-	-
Inscription		-	-	-	-	-	-	-	-	-
Father	Charles C. Hopkins (1801-1894)	-	-	-	-	-	-	-	-	-
Mother		-	-	-	-	-	-	-	-	-
Spouses	Mary A Eaton Hopkins (1836-1922) Florence E. Minich Hopkins (1850-1920)	David S. Hopkins (1834-1918)	-	-	-	-	-	-	-	-
Children	George Hopkins (1859-1933) Irving F Hopkins (1861-1919) Charles Henry Hopkins (1865-1928)		-	-	-	-	-	-	-	-
-		-	-	-	-	-	-	-	-	-
Memorial #	116548389	115052566	-	-	-	-	-	-	-	-

See FindaGrave for data on children. 

10.  Anon.  1889/1900.  Grand Rapids City Directory, 1889/1900.  R.L. Polk and Co., Grand Rapids, MI (online at Ancestry.com):

Name:	David S Hopkins	David S Hopkins
Location 1:	17 Old Aldrich blk	74 Monroe
Location 2:	113 Paris avenue	113 Paris avenue
Occupation:	architect	Architect and Publisher Architectual Books
Year:	1889	1890
City:	Grand Rapids	Grand Rapids
State:	MI	MI

11.  Hackley & Hume Historic Site (online at the Muskegon County Museum web site [link died]):  our subject was apparently an architect of some note.

12.  Hume House and Hackley House (online at the Michigan Historical Markers web site). 

13.  WorldConnect / WorldTree (online at RootsWeb.com/Ancestry.com, respectively).