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Diana, Goddess of the Hunt for Ancestors!
 
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Robert Rush SPEDDEN
Melcina Elizabeth THOMPSON
Husband:  Robert Rush SPEDDEN
Birth:  1822/3, MD
Occupation:  physician
Marriage:  13 Dec 1842, Pettis Co., MO
Wife:  Melcina Elizabeth THOMPSON
Birth:  25 May 1824, Scott? Co., KY
Death:  Jun 1900, San Jose, Santa Clara Co., CA 
Occupation:  homemaker
Father:  Gen. David THOMPSON
Mother:  Elizabeth "Betsy" SUGGETT
Children born in Pettis Co., MO:
1.  Eugene SPEDDEN, b. 1843/4
2.  Elizabeth "Lizzy" SPEDDEN, b. 1845/6
3.  Harold F. "Harry" SPEDDEN, b. 1847/8
4.  Clifford SPEDDEN, b. Jun/Jul 1850
Keywords for search engines:  genealogy; USA, US, United States, California, Kentucky, Maryland

Sources:

1.  1850 Pettis County, Missouri, Census (online at the USGenWeb Census Project):  District No. 68, Roll M432-409, pp. 124B-125A, 219/219, enumerated 2 Sep 1850 (extracted by Ceryl Sears; proofread by Shirley Combs):
33 Thompson David 74 M   15,000 Va
34 Thompson Betsey 68 F     Ky
35 Thompson Monroe 29 M Farmer  3,000 Ky
36 Thompson Charlotte 24 F     Va
37 Thompson Melcina  1 F     Mo
38 Spedden Robt. R. 27 M Physician  1,500 Md
39 Spedden Melcena 24 F     Ky
40 Spedden Eugene  6 M     Mo
41 Spedden Lizzy  4 F     Mo
42 Spedden Harry F.  2 M     Mo
 1 Spedden Cliffird 2/12 M     Mo
David & Betsey THOMPSON are Melcina's parents.  They are listed between the households of Jackson QUISENBERRY and Morton THOMPSON

2.  Archives of the THOMPSON-L mailing list (online at RootsWeb.com).

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