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Isaiah HOPKINS
Elizabeth Ann CRAMER
Husband:  Isaiah / Isaac HOPKINS
Birth:  1802/3, NJ
Occupation:  foundry worker
Marriage:  10 Jul 1824
Given Eliza's birthyear, I seriously doubt they married in 1824; the birthyear of her eldest child also supports a later year.
Wife:  Elizabeth / Eliza Ann CRAMER
Birth:  1810, NJ
Occupation:  homemaker
Father:  Isaac CRAMER / CRANMER (1785- ) David4, Jeremiah3, John2, William1
Mother:  Mary VANEMAN, d/o John VAN EMAN
Children:
born in NJ, possibly in Weymouth Twp., Gloucester Co., NJ:
1.  Isaac Cramer HOPKINS, b. 4 Jan 1829

born in NJ or PA:
2.  Ellen HOPKINS, b. 1830-35

born in Franklin Twp., Huntingdon Co., PA:
3.  Roxanna HOPKINS, b. 1834/5
4.  (Daughter) HOPKINS, b. 1835-40; d. by 1850

born in PA, presumably in either Franklin Twp., Huntingdon Co., PA, or Punxsutawney, Young Twp., Jefferson Co., PA
5.  John HOPKINS, b. 1844/5

Said to have had 14 children, but the census does not remotely reflect that number, unless she had a great many infants die young.

Keywords for search engines:  genealogy; USA, US, United States, New Jersey, Pennsylvania

Sources:

1.  LDS.  Family Search: Internet Genealogy Service:  IGI - International Genealogical Index (online at FamilySearch.org).
Isaiah HOPKINS
Birth: About 1810, Millville, Cumberland, New Jersey
Marriage: 10 Jul 1824, Jefferson, Pennsylvania
Spouse: Elizabeth Ann CRAMER
Birth: 1808, Millville, Cumberland, New Jersey
Father: Isaac CRAMER; Mother: Mary VANEMAN
Source: patron submission
Location: Millville, Cumberland, New Jersey
Isaac HOPKINS; Birth: About 1825
Ellen HOPKINS; Birth: About 1827
Roxanna HOPKINS; Birth: About 1828
John HOPKINS; Birth: About 1831
Father: Isaiah HOPKINS; Mother: Elizabeth Ann CRAMER
Source: patron submissions
The censuses indicate that Isaiah was born in 1802/3 in NJ and that Eliza was born in 1810 in NJ.
They had their first child in NJ, so they cannot have married in PA.

2.  The 1790 thru 1820 censuses of New Jersey are missing.

3.  1830 Census Index/Images (online at Ancestry.com, Image #3 of 16; extracted by Diana Gale Matthiesen):
1830 NJ Gloucester Co. Weymouth Twp. Roll 81 p. 174 Ln. 24 Isaiah Hopkins 100 010 - 000 010
These data indicate:
No. & Sex Age Class Therefore Born Individuals Inferred
1 male 4 or under 1825-1830 = Isaac (b. 1829)
1 male 20-29 1800-1810 = Isaiah (b. 1802/3)
1 female 20-29 1800-1810 = Eliza (b. 1810)

4.  1840 Census Index/Images (online at Ancestry.com, Image #5-6 of 16; extracted by Diana Gale Matthiesen):
1840 PA Huntingdon Co. Franklin Twp. Roll 462 pp. 365B-366A Ln. 20 Isaiah Hopkins 001 001 - 120 010 _______
These data indicate:
No. & Sex Age Class Therefore Born Individuals Inferred
1 male 10-14 1825-1830 = Isaac (b. 1829)
1 male 30-39 1800-1810 = Isaiah (b. 1802/3)
1 female 4 or under 1835-1840 = Daughter A
2 females 5-9 1830-1835 = Roxanna (b. 1834/5)
= Ellen
1 female 20-29 1810-1820 = Eliza (b. 1810)

5.  1850 Census Every-Name-Index/Images (online at Ancestry.com, Image #9 of 9):  Punxsutawney, Young Twp., Jefferson Co., PA, Roll M432_786, p. 80B, 90/97, enumerated 2 Aug 1850, official enumeration date 1 Jun 1850 (extracted by Diana Gale Matthiesen):
Isaac Hopkins 47 M   Foundry 30 NJ
Eliza    " 40 F       do
Roxanna  " 15 F       Pa
John     "  5 M       "
Eli Cramer 26 M   Moulder   NJ
George Decay 25 M   Teamster   NY
H Ballard 20 M   Carpenter   Ohio

6.  1860 Census Every-Name-Index/Images (online at Ancestry.com, Image #31 of 33):  Phoenix P.O., Redbank Twp., Armstrong Co., PA, Roll M653_1070 (Book 1), p. 597, PN 31, 198/198, enumerated 22 Jun 1860, official enumeration date 1 Jun 1860 (extracted by Diana Gale Matthiesen):
Isaiah Hopkins 57 M   Moulder   150 NJ
Eliza A   " 51 F   H work     "
John      " 15 M   M lab     Pa
Ella Williams  5 F         "

7.  1870 Census Every-Name-Index/Images (online at Ancestry.com):  not found.

8.  Anon.  1893.  Commemorative Biographical Record of Washington County, Pennsylvania.  J.H. Beers & Co., Chicago. (online at www.chartiers.com).  Excerpt from p. 211:
J. HOWARD CRAMER, editor and proprietor of the Enterprise-Call, Burgettstown, is a son of E. V. and Susan (Weight) Cramer, and was born June 8, 1856, at Spruce Creek, Huntingdon Co., Penn.

The history of the family, of which this gentleman is a conspicuous and honored member, began with Isaac Cramer, who was born near Millville, Gloucester Co., N.J., in 1786.  He was the second child in a large family, and was of English descent, his father having emigrated to this country some time before, the exact date not now being known; but, at any rate, there is evidence that he served as a soldier in the American army during the Revolutionary war.  In 1807 Isaac Cramer married Mary Van Eman, who was born in 1783, a daughter of John Van Eman, a farmer, also of Millville, N.J.  Her parents had emigrated to this country from Wales.  After marriage Mr. Cramer learned the trade of an iron molder.  He was drafted and served through the war of 1812, and after the close of that struggle He moved to Cumberland county, N.J.  In 1832 he went to Lancaster county, Penn., fourteen miles southeast of Lancaster city.  Ten children were born to Mr. and Mrs. Cramer, of whom the following is a brief record...

(2) Eliza Ann was born in 1811, and married Isaiah Hopkins in 1826.  They afterward settled in Jefferson county, Penn.; fourteen children were born to their marriage...

There's no indication in the censuses that our subjects had 14 children.

9.  WorldConnect / Ancestry World Trees (online at RootsWeb.com/Ancestry.com):  the file there spells Elizabeth's surname, "CRANMER."

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