— born in NJ or PA:
2.  Ellen HOPKINS, b. 1830-35

— born in Franklin Twp., Huntingdon Co., PA:
3.  Roxanna HOPKINS, b. 1834/5
4.  (Daughter) HOPKINS, b. 1835-40; d. by 1850

— born in PA, presumably in either Franklin Twp., Huntingdon Co., PA, or Punxsutawney, Young Twp., Jefferson Co., PA
5.  John HOPKINS, b. 1844/5

Said to have had 14 children, but the census does not remotely reflect that number, unless she had a great many infants die young.

1.  LDS.  Family Search: Internet Genealogy Service:  IGI - International Genealogical Index (online at FamilySearch.org).

Isaiah HOPKINS Birth: About 1810, Millville, Cumberland, New Jersey Marriage: 10 Jul 1824, Jefferson, Pennsylvania Spouse: Elizabeth Ann CRAMER Birth: 1808, Millville, Cumberland, New Jersey Father: Isaac CRAMER; Mother: Mary VANEMAN Source: patron submission

Location: Millville, Cumberland, New Jersey Isaac HOPKINS; Birth: About 1825 Ellen HOPKINS; Birth: About 1827 Roxanna HOPKINS; Birth: About 1828 John HOPKINS; Birth: About 1831 Father: Isaiah HOPKINS; Mother: Elizabeth Ann CRAMER Source: patron submissions

The censuses indicate that Isaiah was born in 1802/3 in NJ and that Eliza was born in 1810 in NJ.
They had their first child in NJ, so they cannot have married in PA.

2.  The 1790 thru 1820 censuses of New Jersey are missing.

3.  1830 Census Index/Images (online at Ancestry.com, Image #3 of 16; extracted by Diana Gale Matthiesen):

1830

NJ

Gloucester Co.

Weymouth Twp.

Roll 81

p. 174

Ln. 24

Isaiah Hopkins

100 010 - 000 010

These data indicate:

No. & Sex	Age Class	Therefore Born	Individuals Inferred
1 male	4 or under	1825-1830	= Isaac (b. 1829)
1 male	20-29	1800-1810	= Isaiah (b. 1802/3)
1 female	20-29	1800-1810	= Eliza (b. 1810)

4.  1840 Census Index/Images (online at Ancestry.com, Image #5-6 of 16; extracted by Diana Gale Matthiesen):

1840

PA

Huntingdon Co.

Franklin Twp.

Roll 462

pp. 365B-366A

Ln. 20

Isaiah Hopkins

001 001 - 120 010

_______

These data indicate:

No. & Sex	Age Class	Therefore Born	Individuals Inferred
1 male	10-14	1825-1830	= Isaac (b. 1829)
1 male	30-39	1800-1810	= Isaiah (b. 1802/3)
1 female	4 or under	1835-1840	= Daughter A
2 females	5-9	1830-1835	= Roxanna (b. 1834/5) = Ellen
1 female	20-29	1810-1820	= Eliza (b. 1810)

5.  1850 Census Every-Name-Index/Images (online at Ancestry.com, Image #9 of 9):  Punxsutawney, Young Twp., Jefferson Co., PA, Roll M432_786, p. 80B, 90/97, enumerated 2 Aug 1850, official enumeration date 1 Jun 1850 (extracted by Diana Gale Matthiesen):

Isaac Hopkins	47	M		Foundry	30	NJ
Eliza    "	40	F				do
Roxanna  "	15	F				Pa
John     "	5	M				"
Eli Cramer	26	M		Moulder		NJ
George Decay	25	M		Teamster		NY
H Ballard	20	M		Carpenter		Ohio

6.  1860 Census Every-Name-Index/Images (online at Ancestry.com, Image #31 of 33):  Phoenix P.O., Redbank Twp., Armstrong Co., PA, Roll M653_1070 (Book 1), p. 597, PN 31, 198/198, enumerated 22 Jun 1860, official enumeration date 1 Jun 1860 (extracted by Diana Gale Matthiesen):

Isaiah Hopkins	57	M		Moulder		150	NJ
Eliza A   "	51	F		H work			"
John      "	15	M		M lab			Pa
Ella Williams	5	F					"

7.  1870 Census Every-Name-Index/Images (online at Ancestry.com):  not found.

8.  Anon.  1893.  Commemorative Biographical Record of Washington County, Pennsylvania.  J.H. Beers & Co., Chicago. (online at www.chartiers.com).  Excerpt from p. 211:

J. HOWARD CRAMER, editor and proprietor of the Enterprise-Call, Burgettstown, is a son of E. V. and Susan (Weight) Cramer, and was born June 8, 1856, at Spruce Creek, Huntingdon Co., Penn. The history of the family, of which this gentleman is a conspicuous and honored member, began with Isaac Cramer, who was born near Millville, Gloucester Co., N.J., in 1786.  He was the second child in a large family, and was of English descent, his father having emigrated to this country some time before, the exact date not now being known; but, at any rate, there is evidence that he served as a soldier in the American army during the Revolutionary war.  In 1807 Isaac Cramer married Mary Van Eman, who was born in 1783, a daughter of John Van Eman, a farmer, also of Millville, N.J.  Her parents had emigrated to this country from Wales.  After marriage Mr. Cramer learned the trade of an iron molder.  He was drafted and served through the war of 1812, and after the close of that struggle He moved to Cumberland county, N.J.  In 1832 he went to Lancaster county, Penn., fourteen miles southeast of Lancaster city.  Ten children were born to Mr. and Mrs. Cramer, of whom the following is a brief record... (2) Eliza Ann was born in 1811, and married Isaiah Hopkins in 1826.  They afterward settled in Jefferson county, Penn.; fourteen children were born to their marriage...

There's no indication in the censuses that our subjects had 14 children.

9.  WorldConnect / Ancestry World Trees (online at RootsWeb.com/Ancestry.com):  the file there spells Elizabeth's surname, "CRANMER."