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DNA Siblingship Tests a Sample Case
The question was raised whether one of four siblings had a different father than the other three.  Siblingship tests were run between A, the child in question, and her brothers, B and C.  Then another test was run comparing A to her sister, D.  Results between A and B showed that she was 27 times more likely to be his sister, than not.  Results comparing A to C and D were deemed "inconclusive," which here means not certainly yes or no (i.e., the inconclusive results do not falsify the hypothesis of relationship).  As there is no doubt that B, C, and D are full siblings, and there is no doubt that A and B are siblings, then logically, all four must be full siblings.

Each parent provides two copies of each marker; therefore, there can be no more than four different values for any one marker among the children.  In no case, below, do the siblings collectively possess more than four different values at any one marker.  The hypothesis of siblingship is supported (i.e., not falsified) by these results.

Protocol Chromosome Marker   A   B   C   D   Parental
Values
SGM
(n=6)
SGM+
(n=10+1)
CODIS
(n=13+1)
# Location
  X   2 q35-37.1 D2S1338   19 23   17 17   17 23   17 17   17, 17, 19, 23
    X 2 p23-2p645 TPOX   8 8   8 11   8 8   8 11   8, 8, 11
  X X 3 p21 D3S1358   15 16   16 16   15 16   15 16   15, 16, 16
X X X 4 q28 FGA   23 24   20 21   23 24   23 24   20, 21, 23, 24
    X 5 q21-q31 D5S818   12 12   12 12   12 12   12 12   12, 12
    X 5 q33.3-34 CSF1P0   10 11   10 11   12 12   10 12   10, 11, 12, 12
    X 7 q D7S820   10 11   10 11   10 11   10 12   10, 11, 12
X X X 8 q24.1-24.2 D8S1179   10 13   10 13   14 14   10 14   10, 13, 14
X X X 11 p15.5 TH01   6 6   6 9.3   6 9.3   6 6   6, 6, 9.3
X X X 12 p12-pter VWA   16 17   14 15   14 15   15 17   14, 15, 16, 17
    X 13 q22-q31 D13S317   7 9   9 12   7 14   9 12   7, 9, 12, 14
  X X 16 p24-qter D16S539   13 10   10 9   9 9   9 13   9, 9, 10, 13
X X X 18 q21.3 D18S51   11 12   11 12   12 12   11 14   11, 12, 12, 14
  X   19 q12-13.1 D19S433   14 14   14 15   14 15   14 15   14, 14, 15
X X X 21 q11.2-q21 D21S11   30 33.2   30 33.2   30 33.2   28 30   28, 30, 33.2
  X X X p22.1-22.3 AMEL   X X   X Y   X Y   X X    
Y p11.2
Legend
Values possessed by Daughter A and shared by her siblings.
Values possessed by the siblings, but not shared with Daughter A.
Values possessd by C and D only.
Values possessed by one sibling only, so not shared with anyone.
Notes
1.  All markers are STR (short tandem repeat) tests on autosomal chromosomes, except for the amelogenin test to determine gender.
2.  CODIS = Combined DNA Index System; DNA profiling system for the US Federal Bureau of Investigation (FBI).
3.  SGM(+) = Second Generation Multiplex (Plus); DNA profiling system for the UK National Criminal Intelligence DNA Database.

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