Jacob and Hester are said to have died after 1880, but I can't find them in the 1880 census.

1a.  Marriage Index:  Ohio, 1789-1850 (Broderbund CD-400):

Cupp, Hester A.

Shaffer, Jacob H.

Nov 15, 1842

Delaware Co.

1b.  Jordan R. Dodd, ed.  1998.  Marriage Index: Ohio, 1851-1900.  Liahona Research, Orem, UT (Broderbund CD-236):  childrens' marriages not found, but then, there are no Morrow County records on this CD.

2.  Cynthia Herrin, ed.  1999.  Morrow County, Ohio, Vital Records.  Ancestry, Inc., Orem UT (online at Ancestry.com):

Name:	Cupp, Hester Ann
Birth Place:	Pickaway Co., OH
Birth Date:	1820
Father's Name:	Conrad Cupp
Mother's Name:	Elizabeth Cruniger
Spouse:	Jacob Shafer
Marriage Date:	Nov 14, 1841
Marriage Location:	Marion Co., OH
Children:	Mary, Helen, Barbara, William, Nancy[,] Sarah, Jacob, Lucetta, Minnie, and three others

3.  Census Index:  U.S. Selected Counties, 1840 (Broderbund CD-316):  I cannot find William or Sarah SHAFER (or variations) in

3.  1850 Census Index/Images (online at Ancestry.com; Image #12 of 30):  Richland Twp., Marion Co., OH, p. 123A/245, 782/789, enumerated 4 Sep 1850 (extracted to Diana Gale Matthiesen):•

Jacob Shafer	32	m	Farmer	1000	O
Hester   "	29	f			O
Mary E   "	7	f			O
Ellen M  "	6	f			O
Barbara  "	4	f			O
William  "	3/12	m			O

Living next door to Julia Anna (CUPP) DUNKLEBERGER, who is almost certainly Hester's sister. 

4.  1860 Census Images (online at Ancestry.com; Image #14 of 48):  Cardington P.O., Cardington Village, Morrow Co., OH, p. 88A, PN 103, 772/758, enumerated 29 Jun 1860 (extracted by Diana Gale Matthiesen):•

Jacob Shafer	42	M		Farm Labor	900	245	Ohio
Hestann  "	39	F					"
Mary     "	17	F					"
Ellen    "	16	F					"
Barbara  "	13	F					"
William  "	11	M					"
Nancy    "	10	F					"
Sarah    "	8	F					"
Andrew   "	6	M					"
Lucetta  "	2	F					"

5.  1870 Census Images (online at Ancestry.com; Image #13 of 24):  Mt. Gilead P.O., Gilead Twp., Morrow Co., OH, p. 373A, PN 13, 99/100, enumerated 29 Jun 1870 (extracted by Diana Gale Matthiesen):•

Shafer Jacob	54	M	W	Farmer	6270	900	Ohio
______ Esther A	50	F	W	Keeping house			Ohio
______ Mary E	26	F	W	School Teacher			Ohio
______ Ellen M	24	F	W	at home			Ohio
______ Barbary A	22	F	W	School Teacher			Ohio
______ William	20	M	W	at home			Ohio
______ Nancy	18	F	W	at home			Ohio
______ Sarah	17	F	W	Attending School			Ohio
______ Andrew J	15	M	W	at home			Ohio
______ Lucetta F	11	F	W	Attending School			Ohio

6.  Census Index:  U.S. Selected Counties, 1880 (Broderbund CD-320):  can't find.

7.  Paul J. Midlam & Barbara Midlam.  1985.  Marion County, Ohio, Cemetery Inscriptions (online at Heritage Pursuit):

SHAFER, Abraham

d Jul 23 1846 Aged: 5m 22d

s/o Jacob H. & Hester A.

Smith [Cemetery]

Richland [Twp.]

8.  Birthdate calculated using Ben Buckner's JavaScript Birthday Calculator.

Entered		Result
23 Jul 1846	22d 5m 0y	1 Feb 1846
(Calculated birthdates should always be prefaced with "ca." — you can't be certain the person who calculated their age did it correctly.)

9.  Anon.  1880.  History of Morrow County, Ohio.  O.L. Baskin & Co., Historical Publishers, Chicago (online at Heritage Pursuit).  On p. 556, under the heading, "Gilead Township":

JACOB H. SHAFER, farmer and stock-raiser; P.O. Cardington; was born in Delaware, now Morrow Co., Ohio, about the year 1815, and lived there until he was 25 years of age; he then moved to Marion Co. and farmed there for fourteen years; thence to Cardington, where he followed teaming and farming, until 1868, when he came to his present place, and has lived there since.  Nov. 24, 1841, he married Miss Hester Ann Cupp; she was born in Pickaway Co., and moved to Crawford Co., and lived there until she was 17 years old, when she went to Delaware Co., and lived there until her marriage.  They had twelve children, eight of whom are living, viz. Mary E., now Mrs. Albright, Van Wert Co., Ohio; Helen M., now Mrs. Lewis, of Morrow Co., Ohio; Barbara A. at home; Wm. S., Morrow Co., Ohio; Nancy, now Mrs. Loffer, Morrow Co., Ohio; Sarah C., now Mrs. Lucas, Marion Co., Ohio; Jacob A., Morrow Co., Ohio; Lucetta F., now Mrs. Kisling, Morrow Co., Ohio; also Minnie F., adopted in infancy.  Mr. Shafer has always been a hard-working man and has earned all he has by his own labor and management.  He owns 113 acres located two miles southeast of Mt. Gilead.  His parents, William and Sallie (Dewitt) Shafer, were natives of Pennsylvania, they married there, and came to Delaware Co., Ohio, in the year 1810; he enlisted and served during the war of 1812, after which he moved to Cass Co., Ind., where he died; his wife died in Marion Co., Ohio, previous to his going West.  Mrs. Shafer's parents, Conrad and Elizabeth (Cruninger) Cupp, were natives of Pennsylvania; they married there, and moved to Pickaway Co. at an early day, and in 1824, they moved to Crawford Co., where they died.

They were married in 1842, at least according to an extraction of the county marriage records.