Thomas ISBELL
Martha Caroline HILL
Husband:  Thomas ISBELL
Birth:  ca. 1810s
Death:  1840s
Father:  Joseph ISBELL (1784-1851)
Marriage:  29 Dec 1838, Cape Girardeau Co., MO
Wife:  Martha Caroline HILL
Birth:  12 Jan 1821, Cape Girardeau Co., Missouri Territory [now MO]
Other Spouse:  m2. 6 Jul 1843, Cape Girardeau Co., MO, Benjamin PENN
Father:  Ezekiel HILL
Mother:  Rachael BLOUNT
Children — born in MO:
1.  Joseph ISBELL, b. 1839/40
2.  William ISBELL, b. 1841/2
Keywords for search engines:  USA, United States, Missouri

Sources:

1.  LDS.  Family Search: Internet Genealogy Service:  IGI - International Genealogical Index (online at FamilySearch.org).
Thomas ISBELL
Spouse: Martha C. HILL
Marriage: 29 Dec 1838, Cape Girardeau, Missouri
Source: Marriage Records, 1805-1950. Cape Girardeau County (Missouri). Recorder of Deeds

2.  1840 Census Index/Images (online at Ancestry.com):  can't find. 

3.  1850 Census Every-Name-Index/Images (online at Ancestry.com, Image #27-28 of 67):  District 92, Scott Co., MO, Roll M432_419, pp. 172A-172B, 210/210, enumerated 5 Sep 1850, official enumeration date 1 Jun 1850 (extracted by Diana Gale Matthiesen):
Benjamin Penn 50 M   farmer   Tennessee
Martha 30 F       Missouri
Catharine 20 F       Tennessee
Richard 15 M   farmer   Kentucky
Joseph 10 M       Missouri
William  8 M       "
Benjamin  6 M       "
[next page]
Dorcas Penn  4 F       Missouri
Mary  3 F       "
Martha Ann  1 F       "
Joseph and William are Martha's children from her first marriage.  Listed three households from Martha's brother, Thomas Green HILL.

4.  1860 Census Every-Name-Index/Images (online at Ancestry.com):  William ISBEL (æ 16) is living in Moreland Twp., Scott Co., MO (p. 41), with the HALE family.

5.  WorldConnect / Ancestry World Trees (online at RootsWeb.com/Ancestry.com).

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