"Jeanette" is the nickname for the English given name, "Jean"; "Jeannette" is the nickname for the French given name, "Jeanne."

1.  Iowa Marriages to 1850 (online at Ancestry.com):

Hopkins, Miles S.

Wade, Jennette

28 Jul 1847

Des Moines Co.

2a.  Census Index:  U.S. Selected Counties, 1850 (Broderbund CD-317):

1850	IA	Hopkins, M. S.	Scott Co.	District 4	p. 221
1852	IA	Hopkins, M. S.	Des Moines Co.	Burlington Twp.	p. 19

2b.  1850 Census Index/Images (online at Ancestry.com; Image #109 of 143):  District No. 4, Scott Co., IA, Roll M432_188 (Book 1), p. 221A,  740/782, enumerated 9 Oct 1850, official enumeration date 1 Jun 1850 (extracted by Diana Gale Matthiesen):

M S Hopkins	24	M		Tailor		Penna
S J    "	19	F				Illinois
Lois A "	4/12	F				Iowa
Jane Wade	17	F				Illinois

Miles is the only HOPKINS indexed in Scott County.

3.  1860 Census Index/Images (online at Genealogy.com, Image #26 of 37):  Burlington P.O., Burlington Twp., Des Moines Co., IA, Roll 319 (Book 1), p. 739, PN 199, 1576/1516, enumerated 18 Jul 1860, official enumeration date 1 Jun 1860 (extracted by Diana Gale Matthiesen):

Miles Hopkins	35	M		Farmer	10000	500	Pennsylvania
Salinda  "	29	F					Illinois
Lois A   "	10	F					"
James E  "	3	M					"
Mary     "	1	F					"

4.  1870 Census Index/Images (online at Genealogy.com, Image #10 of 68):  Hollister P.O., San Juan Twp., Monterey Co., CA, Roll 74 (Book 1), p. 389B, PN 10, 88/90, enumerated 20 Jul 1870, official enumeration date 1 Jun 1870 (extracted by Diana Gale Matthiesen):

Hopkins M S	44	M	W	Farmer	500	200	Pennsylvania
_______ S J	40	F	W	Keeping house			Illinois
_______ Louis A	21	F	W	at home			Iowa
_______ James E	14	M	W	at home			Iowa
_______ Hettie M	12	F	W	at home			Iowa
_______ Ida J	7	F	W				Iowa

5.  1880 Census (indexed at FamilySearch.org; page image online at Ancestry.com, Image #30 of 32):  Soledad, Monterey Co., CA, Roll T9-0069 (Book 1), p. 220B, PN 30, SD 4, ED 55, enumerated 22 Jun 1880, official enumeration date 1 Jun 1880 (extracted by Diana Gale Matthiesen):

1880:  for an explanation of the column headings, please see What the Numbers in the Federal Census Mean (missing columns contained no data).
1	2	3	4	5	6	8	10	13	24	25	26
227	233	Hopkins M S	W	M	54		/	Farmer	Penn	Penn	Penn
		_______ Jeannette	W	F	50	Wife	/	Keeps house	Ills	Ala	NY

6.  1890 Census:  the 1890 Census Population Schedules were destroyed.

7.  Anon.  1882.  History of Scott County, Iowa.  Inter-State Publ. Co., Chicago (excert posted by Deborah Gerischer to the Scott County, Iowa, message board online at Ancestry.com / RootsWeb.com).  Biographical sketch of our subject's brother, Samuel G. HOPKINS.

8.  Messages in the California Forum (online at GenForum.com).

9.  WorldConnect / Ancestry World Trees (online at RootsWeb.com/Ancestry.com).