1.  Jordan R. Dodd, ed.  1993.  North Carolina Marriages:  Early to 1850.  Liahona Research, Orem, UT (Broderbund CD-229):  not found.

2.  1840 Census Images:  Randolph Co., NC (online at the Randolph County NCGenWeb site).

1840

NC

Randolph Co.

p. 69A

John Hopkins

000 001 - 100 010

These data indicate:

No. & Sex	Age Class	Therefore Born	Individuals Inferred
1 male	30-39	1800-1810	= John (b. 1804/5)
1 female	4 or under	1835-1840	= Annis (b. 1839)
1 female	20-29	1810-1820	= Christina

Listed two lines above John's brother, Martin HOPKINS, who is listed next to their father, Edward "Ned" HOPKINS. 

3.  1850 Census Index/Images (online at Ancestry.com; Image #103 of 125):  Montgomery Co., NC, p. 152B, 735/737, enumerated 26 Sep 1850, official enumeration date 1 Jun 1850 (extracted by Diana Gale Matthiesen):

John Hopkins	45	M		Farmer		No Carolina
Christena "	33	F				"
Annis J   "	10	F				"
Eli P     "	5	M				"
Martin    "	2	M				"

4.  1860 Census Index/Images (online at Genealogy.com, Image #158 of 385):  Ashboro P.O., Western Division, Randolph Co., NC, p. 217B/436, PN 158, 1178/1163, enumerated 15 Aug 1860, official enumeration date 1 Jun 1860 (extracted by Diana Gale Matthiesen):

John Hopkins	56	M		Mine L.		100	NC
Christana "	44	F		h.			"
Jane      "	19	F		"			"
Eli       "	14	M					"
Martin    "	11	M					"
Martha    "	8	F					"

5.  1870 Census Index/Images (online at Genealogy.com, Image #4 of 12):  Jackson Hill P.O., Alleghany Twp., Davidson Co., NC, Roll 1134 (Book 1), p. 2B, PN 4, 26/26, enumerated 29 Jul 1870, official enumeration date 1 Jun 1870 (extracted by Diana Gale Matthiesen):

Hopkins John	56	M	W	Farm laborer		100	NCarolina
_______ Cristena	52	F	W	Keeping house			NCarolina
_______ Martha	20	F	W	At home			NCarolina

John should be 66, not 56.

6.  1880 Census Index/Images (online at Ancestry.com, Image #19 of 22):  New Hope Twp., Randolph Co., NC, p. 193C, PN 19, SD 2, ED 223, enumerated 24 Jun 1880, official enumeration date 1 Jun 1880 (extracted by Diana Gale Matthiesen):

1880:  for an explanation of the column headings, please see What the Numbers in the Federal Census Mean (missing columns contained no data).
1	2	3	4	5	6	8	10	13	24	25	26
196	205	Hopkins John	W	M	76		/	Farmer	NC	NC	NC
		_______ Christenia	W	F	63	Wife	/	Keeping House	"	"	"

Listed three households from John's brother, Martin HOPKINS; and, in the other direction, listed five households from John's brother, Joseph Alexander HOPKINS. 

7.  1890 Census:  the 1890 Census Population Schedules were destroyed.

8.  Anon.  2003.  The Heritage of Montgomery County, North Carolina.  Vol. III.  Montgomery County Historical Society (excerpt posted to the Hopkins Family Genealogy Forum, online at GenForum.com).  In Vol. III, on p. 384, is a biographical sketch of Benjamin HOPKINS, said here to be the father of Edward "Ned" HOPKINS, but the article contains many errors, so caveat emptor!

... Edward “Ned” Hopkins was born in 1772, and in 1801 he married Hannah Crow...  Ned and Hannah had ten children... John Calvin Hopkins (1804-1881) married Christina Harris...