Samuel is said to have been born in Scott Co., VA, but I have found no primary source to document that assertion.

1.  Jordan R. Dodd, ed.  1998.  Marriage Index: Missouri, 1851-1900.  Liahona Research, Orem, UT (Broderbund CD-234):

Eakin, Samuel

Stroup, Clara

29 Sep 1869

Jefferson Co.

2.  1840 Census Index/Images (online at Ancestry.com):  there is a Samuel AKIN (æ 20-30) in Pulaski Co., MO, and there is a Samuel EAKIN (æ 30-40) in Botetourt Co., VA.  These are the only Samuel EAKIN/etc. I can find indexed in the Missouri or Virginia censuses.

3.  1850 Census Every-Name-Index/Images (online at Ancestry.com):  there is a Samuel EAKIN (æ 39, b. VA) in Camden Co., MO, but see email quoted below.  I can find no other Samuel EAKIN/etc. indexed in the entire U.S. census.

4.  1860 Census Every-Name-Index/Images (online at Ancestry.com):  there is a Samuel EAKIN (æ 49, b. VA) in Camden Co., MO, but see email quoted below.  I can find no other Samuel EAKIN/etc. indexed in the entire U.S. census.

5.  1870 Census Every-Name-Index/Images (online at Ancestry.com, Image #4 of 47 — indexed "Arken"):  Hillsboro P.O., Joachim Twp., Jefferson Co., MO, Roll M593_783, p. 246B, PN 4, 26/26, enumerated 13 Jun 1870, official enumeration date 1 Jun 1870 (extracted by Diana Gale Matthiesen):¤•

Eaken Samuel	59	M	W	Retail Grocer	2500	80	Virginia
_____ Clara	37	F	W	Keeps house			Missouri
Hobbs Mollie	17	F	W	Domes Serv't			"

6.  1880 Census Every-Name-Index/Images (online at Ancestry.com, Image #11-12 of 58):  Hematite, Joachim Twp., Jefferson Co., MO, Roll T9_695 (Book 1), pp. 66A-66B, PN 13-14, SD 1, ED 192, enumerated 7 Jun 1880, official enumeration date 1 Jun 1880 (extracted by Diana Gale Matthiesen):¤•

1880:  for an explanation of the column headings, please see What the Numbers in the Federal Census Mean (missing columns contained no data).
1	2	3	4	5	6	8	9	10	13	24	25	26
103	114	Aekens Samuel	W	M	69			/	Farmer	Va	Va	Va
		______ Clara	W	F	47	Wife		/	Keeps house	Mo	Pa	Ky
[next page]
		Aikens Samuel	W	M	9	Son	/			Mo	Va	Mo

7.  1890 Census:  the 1890 Census Population Schedules were destroyed.

8.  1900 Census Every-Name-Index/Images (online at Ancestry.com):  can't find Clara.  Sam AKINS (æ 29, b. Aug 1870, MO/TN/MO; grocer) is unmarried and living in Joachim Twp., Jefferson Co., MO (p. 75A).

9.  WorldConnect / Ancestry World Trees (online at RootsWeb.com/Ancestry.com).

10.  Email from Janet EAKINS.

...I feel that the Samuel Eakin you have in the 1860 census for Auglaize Twp. Camden Co. MO is the Samuel Eaken that shows up in the Civil War records as having been arrested for giving help to the other side, going to prison   (Union) and dying there in 1865.  The records show that this Eaken was also born in 1811 in VA, has family in Camden Co., was a farmer, and started buying land in Camden Co. as early as 1849...

It appears Janet is correct, but that leaves us wondering where our Samuel was in the pre-1870 censuses.