1a.  Byron Sistler & Barbara Sistler.  1987.  Early East Tennessee Marriages, Vol. 1, Grooms.  Byron Sistler & Assoc., Inc., Nashville, TN.  On p. 317:

Ruble, John to Catherine Coon 5-28-1820 [Wa]

Ruble, John W. to Mary Hughes 10-12-1859 (10-13-1859) [Ge]

Rubie (sic), Joseph to Harriet Reeves 2-15-1840 (2-20-1840) [Ge]

Ruble, William J. to Jerusha Ruble 8-21-1847 (8-26-1847) [Ge]

Ruble, Solomon H. to Mary Jane Million 4-21-1851 (5-1-1851) [Wa]

Did the clerk make a mistake?  Because Jerusha's maiden name is supposed to be WOOLSEY.

1b.  Byron Sistler & Barbara Sistler.  1987.  Early East Tennessee Marriages, Vol. 2, Brides.  Byron Sistler & Assoc., Inc., Nashville, TN.  On p. 317:

Ruble, Polly to Hiram T. Price 12-19-1840 (12-20-1840) [Ge]

2.  Census Index:  U.S. Selected Counties, 1820 (Broderbund CD-314):  no Washington Co., TN, on CD.

3.  Census Index:  U.S. Selected Counties, 1830 (Broderbund CD-315):

1830 Census	Ruble, John	TN	Washington Co.	p. 13
1832	Ruble, John	TN	Washington Co.

Also in Washington Co.:  John's father, John E. RUBLE, and brother, Henry E. RUBLE; plus Duke, John S., Henry, Margaret, and Martha RUBLE. 

4.  Census Index:  U.S. Selected Counties, 1840 (Broderbund CD-316):  for the state of Tennessee, surnames from the mid-H's through Z are missing from this CD (see my WARNINGs regarding the Broderbund databases).  [Also missing from the database at Ancestry.com.] 

5.  1850 Census Index/Microfilm (online at GenealogyLibrary.com):  9th Division, E District, Greene Co., TN, p. 228B,  enumerated 6 Nov 1850 (extracted by Diana Gale Matthiesen):

1336/1336	William J Rubel	23	M	Farmer	400	Ten
	Jerusah	34	F			Ten
	Sarah C	2	F			Ten
1337/1337	John W Ruble	59	M	Farmer	900	Ten
	Catherine	62	F			Pensylvania
	Solomon H	26	M	Farmer		Ten

6.  Census Index:  U.S. Selected Counties, 1860 (Broderbund CD-318):

1860	Ruble, John	TN	Greene Co.	District 2	p. 13
1860	Ruble, Jerusa	TN	Greene Co.	District 2	p. 13

Has William died? Is Jerusha now a widow?

7.  LDS.  Family Search: Internet Genealogy Service: Ancestral File.

8.  WorldConnect (online at RootsWeb.com).  Says Jerusha's maiden name was WOOLSEY; no indication that she was married to another RUBLE before marrying Joseph.