"Persis" is a female biblical name; it means "Persian woman."

1.  Marriage Record:

2.  1840 Census Index and Digital Images (online at Ancestry.com; Image #55-56 of 69; extracted by Diana Gale Matthiesen):¤•

1840

VA [now WV]

Preston Co.

pp. 234A-234B

Ln. 28

Jacob Cupp

110 010 - 210 100

0100000

no slaves

These data indicate:

No. & Sex	Age Class	Therefore Born	Individuals Inferred
1 male	4 or under	1835-1840	= William (b. 1839)
1 male	5-9	1830-1835	= Son A
1 male	20-29	1810-1820	=
0 male	30-39	1800-1810	= Jacob (b. 1806/7)
2 females	4 or under	1835-1840	= Persis (b. 1837) = Caroline (b. 1835)
1 female	5-9	1830-1835	= Mary (b. 1832/3)
1 female	15-19	1820-1825	=
0 female	30-39	1800-1810	= Clemena (b. 1809/10)
1	person engaged in agriculture

Jacob and Clemena are in the wrong age classes, yet surely these are our subjects.  Listed eight lines below Jacob's father, Leonard CUPP, who is listed two lines below Jacob's brother, John L. CUPP, who is listed one line below Jacob's sister, Eve (CUPP) SILBAUGH. 

3.  1850 Census Index/Images (online at Ancestry.com; Image #235-236 of 278):  45 District, Preston Co., VA [now WV], pp. 455A-455B, 1376/1376, enumerated 28 Oct 1850 (extracted by Diana Gale Matthiesen):

Jacob Cupp	43	M	Farmer	1200	Va
Clamena  "	40	F			"
Paulina J "	15	F			"
Persus    "	13	F			"
Harrison  "	11	M			"
Lear      "	9	M			"
Susan     "	7	F			"
Lydia A   "	5	F			"
Mary      "	17	F			"
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Sarah Cupp	2	F			Virginia

The eldest daughter's name is clearly "Paulina."  The ordering of the children makes you wonder, but I'm going to assume Mary is just accidentally out of order.  Living next door to sister, Sarah (CUPP) BENSON, and four households from brother, John CUPP, who is living next door to their father, Leonard CUPP. 

4.  1860 Census Images (online at Ancestry.com; Image #67 of 336):  Muddy Creek P.O., District No. 2, Preston Co., VA, 444/437, enumerated 6 Jul 1860 (extracted by Diana Gale Matthiesen):

Jacob Cupp	53	M		Farmer	1700	959	Va
Clemena  "	50	F					"
Caroline J "	24	F					"
Perses H   "	22	F					"
William H  "	20	M					"
Lydia A    "	13	F					"
Sarah E    "	11	F					"
Malissa J  "	6	F					"
Ezra Teets "	15	M					"

The eldest daughter's name is clearly "Caroline."  The enumerator had written Lydia's age as 15, then but a three over the five.  There is a ditto mark after Teets, which should not be there, unless he was adoped by the CUPPs.  In 1850, Jacob was living two-doors down from John TEETS, who had son, Ezra (æ 5).